Nutritional Characteristics, Sites of Origin, and Cost of Foods Consumed during School Hours and Their Relationship to Nutritional Status of Schoolchildren in Mexico City.

Access, nutritional characteristics, preferences, and cost can affect food intake at school. A cross-sectional study was performed to determine the nutritional characteristics, sites of origin, and cost of foods consumed during school hours. Three hundred and sixty-nine children from five public elementary schools in Mexico City participated. The children gave information about the foods that they consumed five days out of the week during school hours, including the place of acquisition, cost of the food, and portion size. Anthropometric measurements of height and weight of the children were taken. Caloric consumption and percentage of recommended daily energy intake from food during school hours was determined. Children were 10.9 ± 0.9 years old; 55.6% were girls, 26% were overweight, 23% were obese, and 3.3% were of low height for age. The average calorie intake was 515 kilocalories (kcal) (boys, 535 kcal; girls, 476 kcal, p = 0.051); calorie intake was higher when school meal intakes included foods from home, school, and outside of school. No significant differences were found in calorie intake by children's nutritional status. The cost in Mexican pesos per 100 kcal consumed showed differences according to the nutritional status of the children; it was 4.0 Mexican pesos for children with normal weight and 4.2 and 3.8 pesos in children who were overweight or obese, respectively. The information obtained in this study should be used to provide nutritional guidance. The food portion size intake during school hours should be reduced, and the food should come from one or at most two sites, because each extra food represents an increase in the total kilocalorie intake.

Cut-off points for serum ferritin to identify low iron stores during the first year of life in a cohort of Mexican infants.

The aim of this study was to identify serum ferritin (SF) cut-off points (COPs) in a cohort of healthy full-term normal birth weight infants who had repeated measurements of SF and haemoglobin every 3 months during the first year of life. The study included 746 full-term infants with birth weight ≥2,500 g, having uncomplicated gestations and births. Participants received prophylactic iron supplementation (1 mg/day of iron element) from the first to the 12th month of life and did not develop anaemia during the first year of life. Two statistical methods were considered to identify COPs for low iron stores at 3, 6, 9 and 12 months of age: deviation from mean and cluster analysis. According to the K-means cluster analysis results by age and sex, COPs at 3 and 6 months for girls were 39 and 21 µg/L and for boys 23 and 11 µg/L, respectively. A single COP of 10 µg/L was identified, for girls and boys, at both 9 and 12 months. Given the physiological changes in SF concentration during the first year of life, our study identified dynamic COPs, which differed by sex in the first semester. Adequate SF COPs are necessary to identify low iron stores at an early stage of iron deficiency, which represents one of the most widespread public health problems around the world, particularly in low- and middle-income countries.

Childhood obesity in Mexico: A critical analysis of the environmental factors, behaviours and discourses contributing to the epidemic.

Mexico has the highest prevalence globally for children who are overweight. We conducted a qualitative study to understand childhood obesity in Mexico and the complex factors at play. Data were collected at three elementary schools in a low socio-economic area in Mexico City. Semi-structured interviews were conducted with 60 children, 24 parents and 28 teachers. The children interviewed were between the ages of 8 and 12 years old. Interview texts were analysed using NVivo 9 and 10 and thematic discourse analysis was used. Findings revealed how children's choices around nutrition and physical activity were constrained by their environment and discursive constructions.

Design of an educational strategy based on Intervention Mapping for nutritional health promotion in Child Care Centers.

Early childhood is a critical period for instilling healthy habits to prevent overweight and obesity. This paper describes the development of an educational intervention for the promotion of healthy eating and physical activity among two-to-four-year-old children in public child care centers (CCCs) in Mexico City. Following the Intervention Mapping (IM) protocol, we developed the Bright Futures multidisciplinary intervention. First, a formative research process to identify the personal and environmental determinants of childhood overweight and obesity, behavioral outcomes and performance objectives was conducted. Then, a matrix of change objectives by intersecting the performance objectives with the determinants was integrated. Bright Futures lasted six months and included 24 weekly sessions, each composed of five phases: warm-up, theory, active movements, relaxation, and hydration. Ad hoc interactive teaching materials focused on recreational activities, and formulated plans for the adoption, implementation and process/impact evaluation of the intervention was developed. IM successfully guided the design of a theory-driven and evidence-based intervention for children in CCCs within a socio-ecological and participatory planning framework. This is one of the first studies in Mexico to use IM in the context of CCCs.

Perceptions of childcare staff for preventing overweight in Mexican preschool children: A SWOT analysis.

OBJECTIVE: To identify strengths, weaknesses, opportunities, and threats (SWOT) perceived by childcare staff for preventing childhood overweight. MATERIAL AND METHODS: Qualitative study using an interpretative phenomenological approach; 18 in-depth, semi-structured interviews and 12 focus groups with 89 key informants working in six Mexican public childcare centers (CCC) were conducted. Through content and SWOT analyses, experts further ranked fifty-nine recurrent perceptions regarding healthy feeding and physical activity (PA), using the Delphi method. RESULTS: Strengths: Acknowledgement of the CCC's responsibility in fostering healthy feeding, availability of organizational regulations, and access to PA infrastructure/indoor activities. Weaknesses: Disregard of preschool overweight as a health problem, nu- tritional misperceptions, and perceived risk of child injuries while conducting PA. Opportunities: Willingness to reduce children's access to junk foods, and parental active play with children during weekends. Threats: Limited family nutritional education, and restricted parental time/economic constraints/access to safe public spaces for PA. CONCLUSIONS: The identified SWOT must be considered when developing obesityprevention interventions targeted at CCC.

Perceptions of childcare staff for preventing overweight in Mexican preschool children: A SWOT analysis / Percepciones del personal de guarderías sobre la prevención del sobrepeso en preescolares mexicanos: análisis FODA

Abstract: Objective: To identify strengths, weaknesses, opportunities, and threats (SWOT) perceived by childcare staff for preventing childhood overweight. Materials and methods: Qualitative study using an interpretative phenomenological approach; 18 in-depth, semi-structured interviews and 12 focus groups with 89 key informants working in six Mexican public childcare centers (CCC) were conducted. Through content and SWOT analyses, experts further ranked fifty-nine recurrent perceptions regarding healthy feeding and physical activity (PA), using the Delphi method. Results: Strengths: Acknowledgement of the CCC's responsibility in fostering healthy feeding, availability of organizational regulations, and access to PA infrastructure/indoor activities. Weaknesses: Disregard of preschool overweight as a health problem, nutritional misperceptions, and perceived risk of child injuries while conducting PA. Opportunities: Willingness to reduce children's access to junk foods, and parental active play with children during weekends. Threats: Limited family nutritional education, and restricted parental time/economic constraints/access to safe public spaces for PA. Conclusion: The identified SWOT must be considered when developing obesity-prevention interventions targeted at CCC.

Resumen: Objetivo: Identificar fortalezas, debilidades, oportunidades y amenazas (FODA) percibidas por personal de guarderías, para prevenir sobrepeso en preescolares. Material y métodos: Estudio cualitativo con enfoque fenomenológico interpretativo en seis guarderías públicas de la Ciudad de México. Se realizaron 18 entrevistas semiestructuradas a profundidad y 12 grupos focales con 89 directivos y trabajadores. Mediante análisis de contenido y FODA se identificaron 59 percepciones sobre alimentación y actividad física (AF), jerarquizadas por expertos mediante el método Delphi. Resultados: Fortalezas: Reconocimiento del potencial de guarderías en promover alimentación saludable, disponibilidad de reglamentos y acceso a infraestructura/práctica de AF en interiores. Debilidades: No se considera el sobrepeso infantil como un problema de salud, baja alfabetización nutricional y percepción de riesgo de lesiones al practicar AF. Oportunidades: Voluntad de limitar acceso a alimentos chatarra y estimular a padres e hijos a realizar juegos activos en fines de semana. Amenazas: Limitada orientación alimentaria y restricciones temporales/económicas/de acceso a espacios seguros para AF. Conclusión: Las FODA identificadas deben considerarse en las intervenciones para prevenir el sobrepeso en guarderías.

Energy imbalance and psychosocial imbalance in the construction of child obesity in a marginalized area of Mexico City / Desbalance energético y desbalance psicosocial en la construcción de la obesidad infantil en una zona marginada de la Ciudad de México

Abstract Introduction Child obesity is a growing phenomenon and marginalized communities in Mexico City are not exempt from it. The results achieved by frequent preventive and remedial interventions are still unacceptable. Objective To contribute to the understanding of the growing problem of child obesity and overweight through a community health approach capable of transcending the biological perspective in order to improve interventions. Method We observed and interviewed a sample of school children, some overweight, some obese, and some with a normal BMI. All observations and interviews were carried out in the children's daily environment. We also interviewed some of their mothers. Together with our field notes, we analyzed these testimonies to construct the Grounded Theory that is the output of the present study. Results We found the children and their families immersed in a toxic environment that, through several mechanisms, fosters the consumption of high-density foods and discourages physical activity. We also found that the resources and competencies that families could use to fend off this environment are, at present, very limited. Discussion and conclusion We concluded that the energy imbalance in overweight and obese children's bodies corresponds to an abysmal psychosocial imbalance between the forces that foster obesity and the resources of the families affected by it. Any intervention aimed at preventing obesity must take this psychosocial imbalance into account.

Resumen Introducción La obesidad infantil es un fenómeno creciente del cual no quedan exentas las comunidades marginales de la Ciudad de México. Las intervenciones preventivas y remediales son frecuentes, pero sus impactos todavía no son aceptables. Objetivo Contribuir a la comprensión del fenómeno creciente de la obesidad y el sobrepeso infantil con una visión de salud comunitaria, que trascienda la visión biológica del problema y mejore las intervenciones. Método En su entorno escolar y comunitario observamos y entrevistamos a escolares, unos con obesidad o sobrepeso y otros con índice de masa corporal normal. También entrevistamos a las madres de algunos de ellos. Analizamos estos testimonios y nuestras notas de campo para construir la Teoría Fundamentada producto de este estudio. Resultados Encontramos a los niños y sus familias inmersos en un ambiente tóxico que, por múltiples mecanismos, promueve el consumo de alimentos de alta densidad e inhibe la actividad física. Encontramos también que los recursos y habilidades con que las familias podrían resistir a este ambiente son, por lo pronto, muy reducidos. Discusión y conclusión Concluimos que el desbalance energético en el cuerpo de los niños con sobrepeso corresponde a un enorme desbalance psicosocial entre las fuerzas que promueven la obesidad y los recursos de las familias que la sufren. Toda intervención preventiva debe tomar en cuenta este desequilibrio psicosocial.

Blood toxic metals and hemoglobin levels in Mexican children.

Metal toxicity can cause hematologic abnormalities and hemolysis. To evaluate the relationship of anemia with metal contamination in children, the following elements were quantified in dry blood: silicon, chromium, lead, titanium, vanadium, nickel, arsenic, manganese, and cadmium. A total of 88 samples of anemic children and 208 of non-anemic children aged 6-12 years were analyzed. Lead (35.1%), chromium (24.3%), vanadium (24.3%), nickel (45.6%), and silicon (48.6%) were identified in the samples, with titanium only detected in anemic children. The average level of arsenic was higher in anemic than non-anemic children (0.041 ± 0.11 wt% vs 0.014 ± 0.05 wt%, p < 0.05) and correlated with the concentration of hemoglobin (r = -0.441, p < 0.01). In conclusion, heavy metals, which confer a health risk, were detected in the dry blood of the children evaluated, and the levels of arsenic and titanium were found to be related to anemia.

Efecto de una intervención basada en guarderías para reducir conductas de riesgo de obesidad en niños preescolares / Effect of an intervention based on child-care centers to reduce risk behaviors for obesity in preschool children

Resumen: Introducción: La edad preescolar es una etapa crítica para la promoción de la salud y la prevención de la obesidad, que es un problema emergente de salud pública en la niñez. El objetivo de este trabajo fue diseñar y evaluar el efecto de una intervención multifacética basada en la atención en guarderías para reducir conductas de riesgo de obesidad en niños preescolares. Métodos: Se realizó un ensayo comunitario, aleatorizado por conglomerados, en 16 guarderías del Instituto Mexicano del Seguro Social de la Ciudad de México. El estudio duró 12 meses. Participaron niños entre 2 y 4 años de edad que asistían a las guarderías. La intervención consistió en 12 sesiones educativas semanales interactivas para los niños y seis talleres familiares. Se determinaron cambios de alimentación y actividad física, disponibilidad en el hogar por tipo de alimentos y estilos maternos de alimentación a 6 y 12 meses. Se comparó el cambio por etapa en cada grupo y entre ambos grupos en cada etapa con la prueba χ2. Resultados: Se observó la reducción de disponibilidad en el hogar de algunos alimentos no recomendados y una mayor actividad física en el grupo de intervención. Conclusiones: La mejora en actividad física puede tener efecto en el largo plazo; se requieren estrategias innovadoras que modifiquen las conductas alimentarias de riesgo para obesidad en las familias.

Abstract: Background: Preschool age is a critical stage for health promotion and prevention of obesity, which is an emerging public health problem in children. The aim of this study was to design and evaluate the effect of a multifaceted intervention based on child-care centers to reduce risk behaviors for obesity among preschool children. Methods: A 12-month cluster-randomized community trial was conducted in 16 Mexican Institute of Social Security child-care centers in Mexico City. Children between 2 and 4 years of age enrolled in the selected child-care centers participated in the study. Intervention comprised 12 weekly curriculum sessions for the children, and six family workshops. Changes in children's dietary and physical activity, food availability at home, and maternal feeding styles were determined after 6 and 12 months. Changes within groups among stages, and between groups by stage were analyzed through χ2 test. Results: The intervention showed decrease of home availability for some non-recommended foods and increase in physical activity in the intervention group compared to the usual care group. Conclusions: Improvement in physical activity can be effective in the long term; innovative strategies aimed to modify family dietary risk behaviors are required.

[Effect of an intervention based on child-care centers to reduce risk behaviors for obesity in preschool children]. / Efecto de una intervención basada en guarderías para reducir conductas de riesgo de obesidad en niños preescolares.

BACKGROUND: Preschool age is a critical stage for health promotion and prevention of obesity, which is an emerging public health problem in children. The aim of this study was to design and evaluate the effect of a multifaceted intervention based on child-care centers to reduce risk behaviors for obesity among preschool children. METHODS: A 12-month cluster-randomized community trial was conducted in 16 Mexican Institute of Social Security child-care centers in Mexico City. Children between 2 and 4 years of age enrolled in the selected child-care centers participated in the study. Intervention comprised 12 weekly curriculum sessions for the children, and six family workshops. Changes in children's dietary and physical activity, food availability at home, and maternal feeding styles were determined after 6 and 12 months. Changes within groups among stages, and between groups by stage were analyzed through χ2 test. RESULTS: The intervention showed decrease of home availability for some non-recommended foods and increase in physical activity in the intervention group compared to the usual care group. CONCLUSIONS: Improvement in physical activity can be effective in the long term; innovative strategies aimed to modify family dietary risk behaviors are required.

Preferencias alimentarias y estado de nutrición en niños escolares de la Ciudad de México / Food preferences and nutritional status in school-age children living in Mexico City

Introducción: Durante la niñez es fundamental el desarrollo de prácticas saludables que definan buenos hábitos que perdurarán a lo largo de la vida. El objetivo de este estudio fue identificar las preferencias alimentarias y su variación de acuerdo con el estado nutricional de niños escolares en la Ciudad de México. Métodos: Se realizó un estudio transversal que incluyó a 1,456 niños escolares de ocho escuelas públicas en la Ciudad de México. Los niños respondieron un cuestionario autoadministrado sobre sus preferencias de 70 alimentos seleccionados, y se les realizó antropometría; los padres proporcionaron información sociodemográfica de la familia. Se evaluaron las preferencias de cada alimento con escala tipo Likert y se calcularon las frecuencias para el total de niños y por nivel nutricional. Resultados: La mediana de edad de los niños fue de 9 años. El 48.6% tuvo sobrepeso u obesidad. Los alimentos con mayor preferencia fueron frutas, pizzas, leche con sabor y papas a la francesa (fritas). Los alimentos menos preferidos fueron verduras, cereales integrales, pescado, carnes y queso panela. El agua (72%) y las bebidas azucaradas (71%) tuvieron alta preferencia. No se encontraron variaciones en las preferencias con respecto al estado nutricional. Conclusiones: El patrón de preferencias alimentarias de los niños escolares representa un riesgo para el consumo inadecuado de alimentos y para el aumento en la prevalencia de obesidad en esta población. Se requiere de intervenciones oportunas para promover un entorno alimentario saludable y que las preferencias nutricionales sean adecuadas desde edades tempranas.

Background: Childhood is a basic period for the development of habits and their continuation during the course of life. The objective of this study was to identify food preferences and their variations according to the nutritional status in school-age children living in Mexico City. Methods: A cross-sectional study was carried out including 1465 school-age children attending eight public elementary schools in Mexico City. Children were asked to complete a questionnaire regarding their preferences to 70 selected different foods. Anthropometric measurements were also carried out. Parents of the children provided sociodemographic information. For each food, the preference was evaluated using a Likert scale. Frequencies were calculated for the total sample and for different nutritional status levels. Results: Median age of children was 9 years old. Forty-eight percent of the children were overweight or obese. The most preferred foods were fruits, pizzas, flavored milk, and French fries. The least preferred foods were vegetables, whole-grain cereals, fish, meat, and panela cheese. Plain water (72%) and sugar-sweetened beverages (71%) had a high level of preference. There was no preference variation according to nutritional status. Conclusions: Food preference patterns of school-age children are a risk for unhealthy food consumption as well as for the increase in obesity prevalence in this population. Interventions focused on the promotion of a healthy food environment are necessary, aimed at improving food preferences from early childhood.

Feasibility and impact of Creciendo Sanos, a clinic-based pilot intervention to prevent obesity among preschool children in Mexico City.

BACKGROUND: Mexico has the highest adult overweight and obesity prevalence in the Americas; 23.8% of children <5 years old are at risk for overweight and 9.7% are already overweight or obese. Creciendo Sanos was a pilot intervention to prevent obesity among preschoolers in Instituto Mexicano del Seguro Social (IMSS) clinics. METHODS: We randomized 4 IMSS primary care clinics to either 6 weekly educational sessions promoting healthful nutrition and physical activity or usual care. We recruited 306 parent-child pairs: 168 intervention, 138 usual care. Children were 2-5 years old with WHO body mass index (BMI) z-score 0-3. We measured children's height and weight and parents reported children's diet and physical activity at baseline and 3 and 6-month follow-up. We analyzed behavioral and BMI outcomes with generalized mixed models incorporating multiple imputation for missing values. RESULTS: 93 (55%) intervention and 96 (70%) usual care families completed 3 and 6-month follow-up. At 3 months, intervention v. usual care children increased vegetables by 6.3 servings/week (95% CI, 1.8, 10.8). In stratified analyses, intervention participants with high program adherence (5-6 sessions) decreased snacks and screen time and increased vegetables v. usual care. No further effects on behavioral outcomes or BMI were observed. Transportation time and expenses were barriers to adherence. 90% of parents who completed the post-intervention survey were satisfied with the program. CONCLUSIONS: Although satisfaction was high among participants, barriers to participation and retention included transportation cost and time. In intention to treat analyses, we found intervention effects on vegetable intake, but not other behaviors or BMI. TRIAL REGISTRATION: ClinicalTrials.gov NCT01539070.Comisión Nacional de Investigación Científica del IMSS: 2009-785-120.

[Food preferences and nutritional status in school-age children living in Mexico City]. / Preferencias alimentarias y estado de nutrición en niños escolares de la Ciudad de México.

BACKGROUND: Childhood is a basic period for the development of habits and their continuation during the course of life. The objective of this study was to identify food preferences and their variations according to the nutritional status in school-age children living in Mexico City. METHODS: A cross-sectional study was carried out including 1465 school-age children attending eight public elementary schools in Mexico City. Children were asked to complete a questionnaire regarding their preferences to 70 selected different foods. Anthropometric measurements were also carried out. Parents of the children provided sociodemographic information. For each food, the preference was evaluated using a Likert scale. Frequencies were calculated for the total sample and for different nutritional status levels. RESULTS: Median age of children was 9 years old. Forty-eight percent of the children were overweight or obese. The most preferred foods were fruits, pizzas, flavored milk, and French fries. The least preferred foods were vegetables, whole-grain cereals, fish, meat, and panela cheese. Plain water (72%) and sugar-sweetened beverages (71%) had a high level of preference. There was no preference variation according to nutritional status. CONCLUSIONS: Food preference patterns of school-age children are a risk for unhealthy food consumption as well as for the increase in obesity prevalence in this population. Interventions focused on the promotion of a healthy food environment are necessary, aimed at improving food preferences from early childhood.

Opportunities to Strengthen Childhood Obesity Prevention in Two Mexican Health Care Settings.

BACKGROUND: The purpose of this study was to examine Mexican caregivers' perceptions of the role of primary care in childhood obesity management, understand the barriers and facilitators of behavior change, and identify opportunities to strengthen obesity prevention and treatment in clinical settings. METHODS: We conducted 52 in-depth interviews with parents and caregivers of overweight and obese children age 2-5 years in 4 Ministry of Health (public, low SES) and 4 Social Security Institute (insured, higher SES) primary care clinics in Mexico City and did systematic thematic analysis. RESULTS: In both health systems, caregivers acknowledged childhood overweight but not its adverse health consequences. Although the majority of parents had not received nutrition or physical activity recommendations from health providers, many were open to clinician guidance. Despite knowledge of healthful nutrition and physical activity, parents identified several barriers to change including child feeding occurring in the context of competing priorities (work schedules, spouses' food preferences), and cultural norms (heavy as healthy, food as nurturance) that take precedence over adherence to dietary guidelines. Physical activity, while viewed favorably, is not a structured part of most preschooler's routines as reported by parents. CONCLUSIONS: The likelihood of success for clinic-based obesity prevention among Mexican preschoolers will be higher by addressing contextual barriers such as cultural norms regarding children's weight and support of family members for behavior change. Similarities in caregivers' perceptions across 2 health systems highlight the possibility of developing comprehensive interventions for the population as a whole.

Obesity determinants in Mexican preschool children: parental perceptions and practices related to feeding and physical activity.

BACKGROUND AND AIMS: Obesity represents a major public health problem worldwide. In Mexico, overweight and obesity have increased dramatically, affecting 26% of school-aged children. The aim of this study was to explore perceptions and practices of key obesity determinants among parents of preschool children attending child care centers. METHODS: We conducted five focus groups with 38 parents from six Mexico City child care centers. Inquiry topics were 1) childhood obesity causes and consequences; 2) child feeding practices at the child care center and home; 3) healthful and unhealthful foods for young children; 4) significance of physical activity in childhood; and 5) physical activity-promoting factors and barriers. We analyzed these data using content analysis. RESULTS: We identified a number of barriers to healthful eating, including parental time constraints, permissive feeding styles, unhealthful food preparation practices, lack of knowledge about nutrition, food advertisement, and high availability of unhealthful foods in public places. Facilitators to healthful eating included recognition of childhood overweight prevention and consequences, and healthy food choices. Main barriers to childhood physical activity included influence of young family members to play video games, parental time constraints, street safety, low access to sports facilities, and insufficient communication with child care centers. CONCLUSIONS: Understanding parental views and perceptions of the main factors influencing preschoolers' weight-related behavior can inform home-based or environmental interventions that support healthful eating and regular physical activity.

[Health needs in marginalized urban areas in Mexico]. / Necesidades de salud en áreas urbanas marginadas de México.

OBJECTIVE: To understand the health needs of the population living in Mexico's marginalized urban areas. METHODS: A population-based survey of families residing in poor, urban neighborhoods, in five geographic areas in Mexico (northern, central, southern, south-east, and Mexico City), selected through multistage sampling. Interviews were conducted and anthropometric measurements were taken in the home, and included all members of the participating family. Analysis was carried out on positive health factors, nutrition, reproductive health, health problems, and mental health, and results were disaggregated by age and sex. RESULTS: In all, 24,707 individuals participated. The interviewees were found to have minimal schooling (6 years or less). Only 46.8% had health care coverage, be it public or private. Among the children, 19.8% were malnourished; overweight was prevalent from adolescence onwards. Of adolescents 12-19 years of age, 15.7% were sexually active, but only 57.7% of the males and 41.9% of the females in this age group were using some method of contraception. Of the adults, 5.9% suffered from diabetes and 11.5%, from high blood pressure. In the sample of adolescents, adults, and elderly adults, tobacco use was 21.2%; alcohol consumption, 36.0%; illicit drug use, 9.5%; and depression, 20.2%. CONCLUSIONS: The health needs of people living in Mexico's marginalized urban areas proliferate in the context of a young population with weak ties and little support from family and health services. They face crisis and disease--infant malnutrition, high-risk pregnancy, and addictions--the byproducts of disparities in social progress. The rate of chronic conditions was similar to that of the general population of Mexico.

Necesidades de salud en áreas urbanas marginadas de México / Health needs in marginalized urban areas in Mexico

OBJETIVO: Evaluar las necesidades de salud de la población residente en áreas urbanas marginadas de México. MÉTODOS: Encuesta poblacional a familias residentes en colonias urbanas pobres de cinco regiones geográficas de México (Norte, Centro, Sur, Sureste y Ciudad de México), seleccionadas mediante un muestreo polietápico. Se realizaron entrevistas y mediciones antropométricas en sus domicilios a todos los integrantes de las familias seleccionadas y se analizaron las características de salud positiva, nutrición, salud reproductiva, daños a la salud y salud mental por grupos de análisis formados por edad y sexo. RESULTADOS: Participaron 24 707 personas. En los entrevistados se observó una baja escolaridad (6 años o menos) y solo 46,8 por ciento tuvo cobertura de servicios de salud, ya fuera en instituciones públicas o privadas. De los niños, 19,8 por ciento presentaba desmedro y el sobrepeso predominó a partir de la adolescencia. En los adolescentes de 12 a 19 años, 15,7 por ciento tenía vida sexual activa, pero solo 57,7 por ciento de los hombres y 41,9 por ciento de las mujeres de ese grupo de edad usaban algún método anticonceptivo. De los adultos, 5,9 por ciento padecía diabetes y 11,5 por ciento hipertensión arterial. En la muestra de adolescentes, adultos y adultos mayores, el tabaquismo fue de 21,2 por ciento, el consumo de alcohol de 36,0 por ciento, el uso de drogas de 9,5 por ciento y la depresión de 20,2 por ciento. CONCLUSIONES: La vulnerabilidad sanitaria de las personas que viven en las áreas urbanas marginadas de México se manifiesta en la existencia de una población joven, con pocas redes de apoyo familiar y de servicios de salud, que sufre trastornos y enfermedades, como la desnutrición infantil, el alto riesgo reproductivo y las adicciones en adolescentes y adultos, producto del rezago en el desarrollo social. La prevalencia de enfermedades crónicas fue similar a la de la población mexicana no marginada.

OBJECTIVE: To understand the health needs of the population living in Mexico's marginalized urban areas. METHODS: A population-based survey of families residing in poor, urban neighborhoods, in five geographic areas in Mexico (northern, central, southern, south-east, and Mexico City), selected through multistage sampling. Interviews were conducted and anthropometric measurements were taken in the home, and included all members of the participating family. Analysis was carried out on positive health factors, nutrition, reproductive health, health problems, and mental health, and results were disaggregated by age and sex. RESULTS: In all, 24 707 individuals participated. The interviewees were found to have minimal schooling (6 years or less). Only 46.8 percent had health care coverage, be it public or private. Among the children, 19.8 percent were malnourished; overweight was prevalent from adolescence onwards. Of adolescents 12-19 years of age, 15.7 percent were sexually active, but only 57.7 percent of the males and 41.9 percent of the females in this age group were using some method of contraception. Of the adults, 5.9 percent suffered from diabetes and 11.5 percent, from high blood pressure. In the sample of adolescents, adults, and elderly adults, tobacco use was 21.2 percent; alcohol consumption, 36.0 percent; illicit drug use, 9.5 percent; and depression, 20.2 percent. CONCLUSIONS: The health needs of people living in Mexico's marginalized urban areas proliferate in the context of a young population with weak ties and little support from family and health services. They face crisis and disease-infant malnutrition, high-risk pregnancy, and addictions-the byproducts of disparities in social progress. The rate of chronic conditions was similar to that of the general population of Mexico.

Expression of NK cells activation receptors after occupational exposure to toxics: a preliminary study.

The expression of NK cells activation receptors was assessed by comparative study of two groups of women workers at a chemical reagents factory, located in Zapopan, Jalisco, Mexico. Twenty of them were exposed to environmental toxics identified and quantified by gas chromatography, and 20 women unexposed to toxic substances. The expression of the surface markers CD56+ and CD3+, and of the activation receptors and co-receptors on NK cells was quantified by flow cytometry. To assess the cellular damage produced by chronic exposure to the toxics, the thiobarbituric acid reacting substances (TBARS) generated and the total plasma antioxidizing capacity (TPAC) were quantified in both groups. The exposed women had been exposed at least to 12 volatile toxic compounds, benzene, benz(a)pyrene, ethylbenzene, dimethylbenz(a)anthracene, xylene, toluene, styrene, chloroform, formaldehyde, iodine, chlorine and fluorine. Significant difference between the two groups was in the proportion of CD3 lymphocytes, 72.7+/-10.3% in the unexposed women versus 66.8+/-7.9% in the exposed group (p<0.05). The density of expression of NKG2D and NKp30 receptors was significantly higher in the unexposed women compared to the exposed group: NKG2D were 31.3+/-6.3 and NKp30 were 9.5+/-5.2 in the unexposed women and 5.14+/-2.9 (p<0.01) and 4.6+/-1.9 (p<0.05), respectively in the exposed women. No statistically significant differences were found in the expression of NKp80, NKp46 and 2B4 receptors. The concentration of TBARS was lower in women from the unexposed group than the corresponding data from women of the exposed group. However, no significant difference was observed in TPAC between the two groups studied. The results of this preliminary study suggest that from the five activation receptors and co-receptors of NK cells evaluated (NKp30, NKp46, NKp80, NKG2D and 2B4), only NKp30 and NKG2D receptor expression was diminished in women exposed to toxics when compared with data from unexposed women. These results suggest that the occupational exposure to mixture of toxics is one of the important factors in the diminution of the NK cell receptor expression.

Prevalence of anemia and deficiency of iron, folic acid, and zinc in children younger than 2 years of age who use the health services provided by the Mexican Social Security Institute.

BACKGROUND: In Mexico, as in other developing countries, micronutrient deficiencies are common in infants between 6 and 24 months of age and are an important public health problem. The objective of this study was to determine the prevalence of anemia and of iron, folic acid, and zinc deficiencies in Mexican children under 2 years of age who use the health care services provided by the Mexican Institute for Social Security (IMSS). METHODS: A nationwide survey was conducted with a representative sample of children younger than 2 years of age, beneficiaries, and users of health care services provided by IMSS through its regular regimen (located in urban populations) and its Oportunidades program (services offered in rural areas). A subsample of 4,955 clinically healthy children was studied to determine their micronutrient status. A venous blood sample was drawn to determine hemoglobin, serum ferritin, percent of transferrin saturation, zinc, and folic acid. Descriptive statistics include point estimates and 95% confidence intervals for the sample and projections for the larger population from which the sample was drawn. RESULTS: Twenty percent of children younger than 2 years of age had anemia, and 27.8% (rural) to 32.6% (urban) had iron deficiency; more than 50% of anemia was not associated with low ferritin concentrations. Iron stores were more depleted as age increased. Low serum zinc and folic acid deficiencies were 28% and 10%, respectively, in the urban areas, and 13% and 8%, respectively, in rural areas. The prevalence of simultaneous iron and zinc deficiencies was 9.2% and 2.7% in urban and rural areas. Children with anemia have higher percentages of folic acid deficiency than children with normal iron status. CONCLUSION: Iron and zinc deficiencies constitute the principal micronutrient deficiencies in Mexican children younger than 2 years old who use the health care services provided by IMSS. Anemia not associated with low ferritin values was more prevalent than iron-deficiency anemia. The presence of micronutrient deficiencies at this early age calls for effective preventive public nutrition programs to address them.